Abstract: Endometriosis is an common disease of reproductive age women. The fundament research of endometriosis is more extensive and deep in recent years，screening the specificity virulence gene of EMs，studying the proteome and pain mechanism of EMs， provided the new biological parameter and pathway for the EMs diagnosis. The study of stem cell of EMs，the application of gene therapy， the antiangiogenesis and new type hormone suppressant on EMs，broad the new way for the therapy of EMs. All these facilitate the renovation of clinical diagnosis and reform of treatment in Endometriosis.

Key words: Endometriosis, Diagnosis, Stem cells, Pain measurement, Therapies, investigational