Abstract: Endometrial cancer is one of the most common gynaecological malignancies afflicting the lives and health of the women.Surgery，chemotherapy，and radiation protocols have been established for the treatment of endometrial cancer，however，the treatment for the recurrent patients that have acquired radio-or chemoresistance poses a major challenge for us. Tumor stem cells are defined as a subset of tumour cells with the potential to self-renew and give rise to the differentiated cells that comprise the bulk of the tumour.And the researches about tumor stem cells are just in the ascendant. Emerging evidence indicates that the rare tumor cells with the potentiality of endomrtrial cancer tumor stem cell are likely responsible for the development，progression，metastisis and recurrance of endometrial cancer in the researches about the mechanism of the endometrial cancer. This review is a conclution of the characters and sources of the tumor stem cells，and the research progress on tumor stem cells and its markers in endometrial cancer.

Key words: Neoplastic stem cells, Tumor stem cell assay, Endometrial neoplasms, Tumor markers, biological, RNA-binding proteins