Abstract: Thyroid autoimmune diseases are quite prevalent in women of reproductive age， including hyperthyroidism，hypothyroidism during pregnancy and postpartum thyroiditis. TPOAb，TGAb and TRAb are the important markers of autoimmune thyroid dysfunction. The presence of thyroid dysfunction is associated with some adverse effects on fetal and maternal outcomes. Euthyroid women with positive anti-thyroid antibodies in pregnancy are at increased risks for thyroid insufficiency during pregnancy and postpartum thyroiditis，and should be monitored with TSH and TT4. In addition，the thyroid autoimmunity may be related with infertility and abortion. Early screening，diagnosis and proper treatment may effectively reduce the occurrence of adverse pregnancy outcomes in high risk individuals.

Key words: Thyroid diseases, Pregnancy, Autoantibodies, Infertility, female, Abortion