Research Status and Hotspots of Fertility Preservation in Female Malignant Tumor Patients from 2004 to 2024 in the Web of Science Core Databases

doi:10.12280/gjfckx.20250020

Abstract

Abstract:

Objective: To explore the research hotspots and frontiers in fertility preservation for female malignant tumors worldwide over the past two decades and predict the future research directions in this field. Methods: The relevant literature on fertility preservation in female malignant tumors published from January 1, 2004 to November 30, 2024 was retrieved using the Web of Science Core Collection database. Excel software was used to summarize and categorize the literature, and CiteSpace V6.3.R3 software was employed for visual analysis to explore the current research status and hotspots in this field. Results: A total of 2 046 articles were included in this study. The number of publications on fertility preservation in female malignant tumors from 2004 to 2024 showed an overall upward trend, and the number of articles published from 2021 to 2024 tended to stabilize. Professor Oktay, Kutluk from the United States was the author with the highest number of publications, having published a total of 26 papers. Professor Anderson, Richard A from the United Kingdom had the highest betweenness centrality value (0.12). The United States contributed the highest number of publications, with a total of 679 articles. The Assistance Pub Lique Hopitaux Paris and Harvard University were the institution with the highest number of publications, having published 89 articles. Co-occurrence analysis of keywords revealed that research on fertility preservation techniques, fertility preservation in children and young women, and ethical researches are the current research hotspots. Conclusions: Over the past two decades, research on fertility preservation for female malignant tumors has attracted increasing attention. The study of fertility preservation techniques remains an important research topic in the future, among which the research on related technologies for fertility preservation in children and young women is particularly prominent.

Key words: Bibliometrics, Antineoplastic protocols, Fertility, Infertility, female, Fertility preservation

LIN Huan-yu, SHAO Xiao-guang, LU Xu-hong, WANG Qiu-yue, WEI Wei, TONG Chun-yan. Research Status and Hotspots of Fertility Preservation in Female Malignant Tumor Patients from 2004 to 2024 in the Web of Science Core Databases[J]. Journal of International Obstetrics and Gynecology, 2025, 52(2): 180-186.

Figures/Tables 11

References 25

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排名	发文作者	发文量（篇）	中介中心值
1	Oktay, Kutluk	26	0.05
2	Woodruff, Teresa K	23	0.04
3	Partridge, Ann H	19	0.09
4	Quinn, Gwendolyn P	19	0.07
5	Suzuki, Nao	18	0.00
6	Grynberg, Michael	18	0.00
7	Andersen, Claus Yding	15	0.00
8	Anderson, Richard A	14	0.12
9	Mersereau, Jennifer E	14	0.02
10	Sonigo, Charlotte	13	0.00

排名	发文作者	发文量（篇）	中介中心值
1	Oktay, Kutluk	26	0.05
2	Woodruff, Teresa K	23	0.04
3	Partridge, Ann H	19	0.09
4	Quinn, Gwendolyn P	19	0.07
5	Suzuki, Nao	18	0.00
6	Grynberg, Michael	18	0.00
7	Andersen, Claus Yding	15	0.00
8	Anderson, Richard A	14	0.12
9	Mersereau, Jennifer E	14	0.02
10	Sonigo, Charlotte	13	0.00

排名	国家	发文量（篇）	中介中心值
1	USA（美国）	679	0.05
2	CHINA（中国）	195	0.05
3	ITALY（意大利）	189	0.06
4	FRANCE（法国）	181	0.00
5	GERMANY（德国）	134	0.00
6	CANADA（加拿大）	120	0.21
7	BELGIUM（比利时）	160	0.38
8	JAPAN（日本）	97	0.25
9	NETHERLANDS（荷兰）	97	0.18
10	ENGLAND（英国）	92	0.05

排名	国家	发文量（篇）	中介中心值
1	USA（美国）	679	0.05
2	CHINA（中国）	195	0.05
3	ITALY（意大利）	189	0.06
4	FRANCE（法国）	181	0.00
5	GERMANY（德国）	134	0.00
6	CANADA（加拿大）	120	0.21
7	BELGIUM（比利时）	160	0.38
8	JAPAN（日本）	97	0.25
9	NETHERLANDS（荷兰）	97	0.18
10	ENGLAND（英国）	92	0.05

排名	机构	发文量（篇）	中介中心值
1	Assistance Pub Lique Hopitaux Paris（巴黎公共医院）	89	0.51
2	Harvard University（哈佛大学）	89	0.00
3	Northwestern University（西北大学）	77	0.14
4	University of California System （加利福尼亚大学系统）	76	0.22
5	Institut National de la Sante et de la Recherche Medicale （法国国家健康与医学研究院）	74	0.36
6	Universite Paris Cite （巴黎城市大学）	68	0.07
7	Feinberg School of Medicine （费因伯格医学院）	58	0.09
8	Unicancer（法国癌症中心）	47	0.33
9	Dana-Farber Cancer Institute （丹娜法伯癌症研究院）	47	0.23
10	University of Texas System （德克萨斯大学系统）	46	0.00