Abstract: The incidence of gestational diabetes mellius（GDM） is increasing year by year， adverse pregnancy outcomes are strongly associated with fasting plasma glucose level. With increasing fasting glucose levels， considered a normoglycemia range， the risk of large-for-gestational-age（LGA） neonates and/or macrosomia， primary cesarean section， neonatal hypoglycemia， hyperinsulinemia and later diabetes is increasing. The diagnosis and treatment of GDM， in early pregnancy， may help to improve pregnancy outcomes. Using fasting plasma glucose as a screening test for GDM has been getting attention. It is easy to administer， inexpensive， reproducible and easily accepted by pregnant women. Currently， most results indicate a fair correlation between first-trimester fasting glucose level and glucose challenge test（GCT） and oral glucose tolerance test（OGTT）. Moreover， it can signifinantly decrease the number of OGTTs needed for the diagnosis of GDM. The FPG as a screening test for GDM have a higher value.

Key words: Diabetes, gestational, Blood glucose, Pregnancy outcome, Mass screening, Glucose tolerance test