Journal of International Obstetrics and Gynecology ›› 2018, Vol. 45 ›› Issue (1): 75-79.

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Treatment Progresses on Fertility Preservation and Ovarian Preservation in Young Female with Endometrial Carcinoma

LI Qiu-xia,YU Gui-yuan,JIN Ping   

  1. Affiliated Shenzhen Maternity and Child Healthcare Hospital,Southern Medical University,Shenzhen 518028,Guangdong Province,China
  • Received:2017-10-25 Revised:2018-01-14 Published:2018-02-15 Online:2018-02-15
  • Contact: JIN Ping,E-mail:pingjin66@sina.com E-mail:pingjin66@sina.com

Abstract: Endometrial carcinoma (EC) is one of the three common malignant tumor in female reproductive system. Young child-bearing female with endometrial carcinoma are respectively rare. However, with the increasing incidence of endometrial carcinoma and the changes of living habits, endometrial carcinoma shows the significantly young trend. The standard treatment programs of EC leads women to have permanent loss of fertility and premenopausal women advance into menopause, severely affecting the quality of life of young patients. So young EC women retain fertility preservation or ovarian preservation gradually taken attention. The current programs of fertility preservation include: progesterone, aromatase inhibitors, metformin and other medical treatment and hysteroscopic endometrial cancer resection. Several studies have confirmed that obesity was associated with the occurrence and development of endometrial carcinoma. Ovarian preservation and the weight management in period of treatment of young female with endometrial carcinoma are now discussed in this review.

Key words: Endometrial neoplasms, Antineoplastic protocols, Fertility, Ovarian preservation