Abstract: Pre-eclampsia (PE) is the main pregnancy-specific disease that causes maternal and perinatal death. In recent years, with the improvement of the level of treatment of premature infants, the active treatment of pre-eclampsia after 34 weeks of gestation will get good maternal and perinatal outcomes, but the treatment of early-onset pre-eclampsia patients is still unsatisfactory, so the prediction of pre-eclampsia has become a research hot spot. Studies found that pre-eclampsia is associated with the imbalance of coagulation-fibrinolysis system. In many researches, some factors are used to predict pre-eclampsia, for instance, platelet parameters, coagulation quadruple, PAI-1, vWF, P-selectin, and D-dimer. This article reviews the progress of these indicators to predict pre-eclampsia.

Key words: Pre-eclampsia, Platelet count, Plasminogen activator inhibitor 1, P-selectin, Forecasting