The Mechanism and Research Progress of Resveratrol in Pre-eclampsia

doi:10.12280/gjfckx.20201129

Abstract

Abstract:

Pre-eclampsia is a systemic inflammatory multi-system syndrome originating from placental dysfunction,which seriously threatens the health of both mothers and infants. Resveratrol is a natural polyphenol compound that shows effects on anti-aging, anti-oxidative stress, anti-inflammatory, inducing cell apoptosis and enhancing insulin sensitivity. Resveratrol plays an effective role in the pathophysiological process of pre-eclampsia by inhibiting oxidative stress, resisting inflammation, regulating vascular function, promoting trophoblast cell invasion, and regulating immune function. This article summarizes the potential therapeutic mechanism of Resveratrol in pre-eclampsia, and provides reference for the further research and application of Resveratrol in pre-eclampsia.

Key words: Pre-eclampsia, Oxidative stress, Antioxidants, Resveratrol

WEN Qing, QI Ming-ming, LAI Hui-min, XIE Kai-li, WANG Ming-yuan. The Mechanism and Research Progress of Resveratrol in Pre-eclampsia[J]. Journal of International Obstetrics and Gynecology, 2021, 48(4): 371-375.

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