Journal of International Obstetrics and Gynecology ›› 2022, Vol. 49 ›› Issue (6): 635-639.doi: 10.12280/gjfckx.20220187

• Research on Gynecological Malignancies: Review • Previous Articles     Next Articles

Research Progress of Ovarian Sclerosing Stromal Tumor

WANG Min, LI Jia-hui, CUI Jun-ze, MA Shuai()   

  1. Department of Obstetrics and Gynecology, The Second Hospital of Jilin University, Changchun 130041, China
  • Received:2022-03-17 Published:2022-12-15 Online:2023-01-11
  • Contact: MA Shuai E-mail:916446352@qq.com

Abstract:

Sclerosing stromal tumor of the ovary is a rare clinical benign ovarian tumor with low incidence and unclear etiology. It is more common in young women, mostly with unilateral mass, often visit a doctor due to irregular menstrual bleeding or abdominal mass found in physical examination. Imaging examination showed changes such as "lake island sign", "fast in and slow out" and "centrality enhancement". Histopathology showed unilateral rounded cystic solid mass with "false lobule" as the characteristic lesion. Immunohistochemistry showed positive expression of inhibin, vimentin and actin. The diagnosis is mainly made by histopathology, and imaging examination has important reference value. Preoperative diagnosis is difficult and easily confused with ovarian fibroma, follicular membranous cell tumor, ovarian Kookenberg tumor, granulosa cell tumor, etc. Surgical treatment is the main means of treatment, mostly the affected side tumor resection or adnexectomy. Postoperative prognosis is good and ovarian function can be restored to normal. For the tumor with more nuclear mitosis and necrosis, it is necessary to be alert to the risk of recurrence, and long-term follow-up is recommended.

Key words: Ovarian neoplasms, Sclerosing stromal tumor, Diagnosis, Therapy, Prognosis