Abstract: Gestational trophoblastic neoplasia(GTN) usually occurs in women of reproductive age. It is very sensitive to chemotherapy with a high cure rate of 90%-100%.However,in clinical practice,it is very easy to confuse GTN with many other pregnancy-associated diseases,such as ectopic pregnancy. Hysteroscopy and laparoscopy have an important role in the differential diagnosis of GTN，especially for those uterine cavity lesion with normal HCG.They also can effectively salvage some patients with isolated foci of chemoresistant disease, including resecting the GTN lesion and reducing the total courses of chemotherapy.

Key words: Gestational trophoblastic neoplasia, Differential diagnosis, Treatment, Hysteroscopy, Laparoscopy