Abstract: Objective：Retrospective analysis of comprehensive treatment success patients in recurrent spontaneous abortion（RSA）. To evaluate the safety of mother and infant. Methods：105 cases of RSA patients in Baodi Clinical College of Tianjin Medical University from June 2012 to June 2015, age less than 35 years old, who were early pregnancy hospitalized for comprehensive tocolytic therapy success, were taken as the research object (observation group). Selection over the same period (the length of hospitalization was 9, and the reciprocal third was 3) 105 cases with no history of spontaneous abortion, without tocolytic therapy in our hospital were taken as the control group. All cases were followed up for 12 weeks after birth. Results：In the observation group, the pregnancy induced hypertension and premature rupture of membranes were significantly less than that of the control group(all P＜0.05). There was no significant difference in the incidence of gestational diabetes mellitus, placenta and postpartum hemorrhage between the 2 groups (all P＞0.05). Exclusion of stillbirth and abnormal induced labor, there was no significant difference in the amount of bleeding and amniotic fluid condition between the 2 groups (all P＞0.05). The neonatal scores, male and female ratio, premature birth, great children, neonatal birth defects, 12 weeks of incidence of jaundice were similiar between the two groups(both P＞0.05). There was no significant difference in the quality of term birth between the pregnant week and the term birth weight (mean P＞0.05). Conclusions：Recurrent abortion comprehensive tocolytic therapy is safe and effective, with no adverse effects on maternal, which is worthy of clinical promotion.

Key words: Abortion，recurrent, Pregnancy trimester，first, Infant，newborn, Pregnant women, Comprehensive tocolytic therapy