COVID-19 and Pregnancy

doi:10.12280/gjfckx.20201020

Abstract

Abstract:

COVID-19 was detected in December 2019 and became epidemic in Wuhan, Hubei Province, China. It was defined as a global pandemic by the World Health Organization (WHO) on March 11, 2020. COVID-19 is caused by the new virus labeled SARS-CoV-2. SARS-CoV-2 has been known to be genetically similar to SARS virus (SARS-CoV) but distinct from it. The infection typically presents as a fever and cough. It affects all age groups, including newborns, pregnant women to the elders. In pregnant women with COVID-19, there is no evidence for vertical transmission of the virus, but an increased prevalence of preterm deliveries. The COVID-19 may alter immune responses at the maternal-fetal interface and affect the well-being of mothers and infants. In this review, we focused on the reason why pregnant women are more susceptible to COVID-19 and the potential maternal and fetal complications from an immunological viewpoint.

Key words: SARS virus, Pneumonia, Placenta, Immunity, Pregnancy outcome, Treatment outcome, Novel coronavirus pneumonia, SARS-CoV-2

ZHU Ran-ran, AI Li-min, ZHANG Li-ying. COVID-19 and Pregnancy[J]. Journal of International Obstetrics and Gynecology, 2021, 48(4): 380-384.

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