The Pathogenesis and Treatment Updates of Recurrent Spontaneous Abortion with Immune Type

Journal of International Obstetrics and Gynecology ›› 2011, Vol. 38 ›› Issue (5): 398-401.

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The Pathogenesis and Treatment Updates of Recurrent Spontaneous Abortion with Immune Type

LIU Chang-ming，CONG Lin

Prenatal Diagnosis Center，Department of Obstetrics and Gynecology，the First Affiliated Hospital of Anhui Medical University，Hefei 230022，China

Received:1900-01-01 Revised:1900-01-01 Published:2011-10-15 Online:2011-10-15
Contact: CONG Lin

Abstract

Abstract: The pathogenesis of recurrent spontaneous abortion（RSA）is complex，there are nearly 50% RSA for unexplained reasons. Recurrent spontaneous abortion with immune type is the focus of spontaneous abortion research in recent years. The abnormalities of maternal immune system and decidual microenvironment are correlated with RSA of immune type. The pathogenesis of autoimmune RSA was mainly associated with anti-phosphlipid antibody（APLA），while that of alloimmune RSA was due to the imbalance of multi-kinds of immune cells and cytokines. Currently there are several methods for RSA treatment；none of them was publicly established.

Key words: Abortion, habitual, Autoimmunity, Immune tolerance, Lymphocytes, Cytokines

LIU Chang-ming;CONG Lin. The Pathogenesis and Treatment Updates of Recurrent Spontaneous Abortion with Immune Type [J]. Journal of International Obstetrics and Gynecology, 2011, 38(5): 398-401.

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The Pathogenesis and Treatment Updates of Recurrent Spontaneous Abortion with Immune Type

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