Abstract: Cervical intraepithelial neoplasia （CIN）， a common disease of the cervix in the female adults，lacks of safe and effective conservative treatment at present. Photodynamic therapy（PDT），as a new choice for CIN，has a promising prospect for CIN because of its effectiveness and safety. The efficacy of PDT is associated with the photosensitizers and their concentrations，the time span between the topical application and the light activation of the photosensitizers，parameters of the illumination，operation methods，evaluation methods of the therapeutic effect，and so on. We should deeply research on PDT to make it more effective in the treatment of CIN.

Key words: Cervical intraepithelial neoplasia, Photochemotherapy, Photosensitizing agents, Papillomaviridae