妊娠期糖尿病并发血糖正常型酮症酸中毒一例

doi:10.12280/gjfckx.20240441

国际妇产科学杂志 ›› 2024, Vol. 51 ›› Issue (5): 549-551.doi: 10.12280/gjfckx.20240441

• 产科生理及产科疾病: 病例报告 • 上一篇下一篇

妊娠期糖尿病并发血糖正常型酮症酸中毒一例

陈春兰, 刘海蔚()

570311 海口，海南医科大学附属海南医院（陈春兰）；海南省人民医院/海南医科大学附属海南医院内分泌科（刘海蔚）

收稿日期:2024-05-14 出版日期:2024-10-15 发布日期:2024-10-17
通讯作者: 刘海蔚，E-mail：hndxlhw@126.com
基金资助:
海南省临床医学中心建设资助项目(琼卫医函[2021]276号);海南省自然科学基金高层次人才课题(821RC685)

A Case of Euglycemic Diabetic Ketoacidosis Complicating Gestational Diabetes Mellitus

CHEN Chun-lan, LIU Hai-wei()

Hainan Affiliated Hospital of Hainan Medical University, Haikou 570311, China (CHEN Chun-lan); Department of Endocrinology, Hainan General Hospital/Hainan Affiliated Hospital of Hainan Medical University, Haikou 570311, China (LIU Hai-wei)

Received:2024-05-14 Published:2024-10-15 Online:2024-10-17
Contact: LIU Hai-wei, E-mail: hndxlhw@126.com

摘要/Abstract

摘要：

妊娠期血糖正常型酮症酸中毒（euglycemic diabetic ketoacidosis，eDKA）是妊娠期罕见的致命性急症，可危及胎儿的生命。本文报道1例妊娠期糖尿病孕妇在孕32⁺³周时发生eDKA，经过积极地静脉补液、胰岛素治疗后，酮症酸中毒得以纠正，最终采用赖脯胰岛素+地特胰岛素控制血糖，避免了紧急剖宫产，孕35⁺⁴周时因产科彩色超声提示巨大儿行剖宫产娩出1活女婴，出生体质量4 400 g。

关键词: 糖尿病, 妊娠, 糖尿病酮症酸中毒, 诊断, 治疗, 病例报告

Abstract:

Euglycemic diabetic ketoacidosis (eDKA) during pregnancy is a rare and potentially fatal emergency that can endanger the life of the fetus. This paper reports a case of a pregnant woman with gestational diabetes mellitus who developed eDKA at 32⁺³ weeks of gestation. After active intravenous fluid replacement and insulin therapy, the ketoacidosis was corrected. Blood glucose was subsequently controlled using a combination of insulin lispro and insulin detemir, avoiding the need for an emergency cesarean section. At 35⁺⁴ weeks of gestation, due to obstetric ultrasound indicating macrosomia, a cesarean section was performed, and a live female infant was delivered, weighing 4 400 g.

Key words: Diabetes, gestational, Diabetic ketoacidosis, Diagnosis, Therapy, Case reports

陈春兰, 刘海蔚. 妊娠期糖尿病并发血糖正常型酮症酸中毒一例[J]. 国际妇产科学杂志, 2024, 51(5): 549-551.

CHEN Chun-lan, LIU Hai-wei. A Case of Euglycemic Diabetic Ketoacidosis Complicating Gestational Diabetes Mellitus[J]. Journal of International Obstetrics and Gynecology, 2024, 51(5): 549-551.

参考文献 20

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妊娠期糖尿病并发血糖正常型酮症酸中毒一例

A Case of Euglycemic Diabetic Ketoacidosis Complicating Gestational Diabetes Mellitus

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