发热合并肝功能异常的妊娠期干燥综合征一例

doi:10.12280/gjfckx.20211127

国际妇产科学杂志 ›› 2022, Vol. 49 ›› Issue (4): 452-455.doi: 10.12280/gjfckx.20211127

• 产科生理及产科疾病:病例报告 • 上一篇下一篇

发热合并肝功能异常的妊娠期干燥综合征一例

李佳雯, 李濛, 应豪, 赵婷婷, 殷科, 黄璐()

214002 南京医科大学附属无锡妇幼保健院妇产科（李佳雯,李濛,赵婷婷,殷科,黄璐）;同济大学附属第一妇婴保健院（应豪）

收稿日期:2021-12-08 出版日期:2022-08-15 发布日期:2022-08-19
通讯作者: 黄璐 E-mail:huanglusz@163.com
基金资助:
江苏省333工程人才资助项目(LGY2018015);无锡市双百医疗卫生拔尖人才项目(BJ2020081)

A Case of Sjögren′s Syndrome of Pregnancy Complicated with Fever and Hepatic Insufficiency

LI Jia-wen, LI Meng, YING Hao, ZHAO Ting-ting, YIN Ke, HUANG Lu()

Department of Obstetrics and Gynecology, The Affiliated Wuxi Maternity and Child Health Care Hospital of Nanjing Medical University, Wuxi 214002, Jiangsu Province, China (LI Jia-wen, LI Meng, ZHAO Ting-ting, YIN Ke, HUANG Lu);First Maternity and Infant Hospital Affiliated to Tongji University, Shanghai 200040, China (YING Hao)

Received:2021-12-08 Published:2022-08-15 Online:2022-08-19
Contact: HUANG Lu E-mail:huanglusz@163.com

摘要/Abstract

摘要：

干燥综合征（Sjögren′s syndrome）是一种系统性自身免疫性疾病,不影响女性患者的生育能力,但影响胎儿在宫内的生长发育,导致自然流产和早产。由于鉴别诊断困难,妊娠期首次发病的干燥综合征孕妇易延误治疗,导致疾病加重,出现严重不良母儿结局的风险随之升高。报告1例以发热及肝功能异常为首要表现的原发性干燥综合征患者,旨在总结该疾病的诊断依据及治疗方案,阐述临床监测指标及治疗效果。

关键词: 干燥综合征, 妊娠, 发热, 妊娠结局, 肝功能异常

Abstract:

Sjögren′s syndrome is a systemic autoimmune disease that does not affect the fertility of female patients, but it affects the growth of the fetus in the uterus, leading to spontaneous abortion and preterm birth. Because of the difficulty in differential diagnosis, pregnant women with the first episode of Sjögren′s syndrome pregnancy are more likely to delay treatment, leading to an exacerbation of the disease and an increased risk of serious adverse maternal and child outcomes. This is a case report about primary Sjögren′s syndrome with the first sign of fever and hepatic insufficiency. The purpose is summarizing the diagnostic basis and treatment of this disease, elaborating the clinical monitoring index and therapeutic effect.

Key words: Sjögren′s syndrome, Pregnancy, Fever, Pregnancy outcome, Hepatic insufficiency

李佳雯, 李濛, 应豪, 赵婷婷, 殷科, 黄璐. 发热合并肝功能异常的妊娠期干燥综合征一例[J]. 国际妇产科学杂志, 2022, 49(4): 452-455.

LI Jia-wen, LI Meng, YING Hao, ZHAO Ting-ting, YIN Ke, HUANG Lu. A Case of Sjögren′s Syndrome of Pregnancy Complicated with Fever and Hepatic Insufficiency[J]. Journal of International Obstetrics and Gynecology, 2022, 49(4): 452-455.

图/表 2

参考文献 12

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发热合并肝功能异常的妊娠期干燥综合征一例

A Case of Sjögren′s Syndrome of Pregnancy Complicated with Fever and Hepatic Insufficiency

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