国际妇产科学杂志

国际妇产科学杂志 ›› 2012, Vol. 39 ›› Issue (3): 302-305.

• 论著 • 上一篇    下一篇

妊娠早期环境有害因素的暴露与胚胎停育


陈 俊 , 陈亚琼, 侯海燕, 邹晓萍   

  1. 300162 天津,武警医学院附属医院妇产科
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2012-06-15 发布日期:2012-06-15
  • 通讯作者: 陈亚琼

Environmental Adverse Factors Exposure in Early Pregnancy and Embryo Loss

CHEN Jun，CHEN Ya-qiong，HOU Hai-yan，ZOU Xiao-ping   

  1. Department of Obstetrics and Gynecology，the Chinese People's Armed Police Forces Medical College Affiliated Hospital，Tianjin 300162，China
  • Received:1900-01-01 Revised:1900-01-01 Published:2012-06-15 Online:2012-06-15
  • Contact: CHEN Ya-qiong

PDF (PC)

4748

被引次数

6

摘要： 目的：研究妊娠妇女在妊娠早期环境有害因素的暴露情况与胚胎停育之间的关系，从生活习惯及暴露环境的角度探讨影响胚胎生长发育的可能危险因素。方法：收集2009年4月—2010年4月天津市4家综合性医院计划生育门诊的胚胎停育新发病例，选取同期正常妊娠要求终止妊娠行人工流产术者作为对照，由统一培训的调查员进行问卷调查，收集其妊娠期及妊娠前3个月生活习惯及环境有害物质的暴露情况。对问卷调查表进行统计学分析，通过卡方检验、多元线性回归、Logistic回归探讨胚胎停育的可能环境危险因素及其危险度的大小。结果：妊娠妇女在妊娠期经常做饭、户外交通时间过长、妊娠早期家庭装修、其配偶于妊娠前3个月接触油漆涂料等物质均可能对胚胎发育有不良影响，而学历较高的妊娠妇女发生胚胎停育的危险性相对较低。结论：妊娠早期暴露于交通、烹调及装修产生的环境有害物质对胚胎的正常发育有潜在的威胁。

关键词: 环境污染, 胎儿生长迟缓, 问卷调查, 烟雾, 空气污染, 空气污染, 室内

Abstract: Objective：To study the association between environmental adverse factors exposure and embryo loss in early pregnancy， explore the probable risk factors for embryo growth and development and embryo abortion on life style and environmental aspect. Methods：Collect the new cases of embryo loss in four general hospitals of Tianjin from April 2009 to April 2010，select the women that have the request for abortion operation in normal pregnancy as control. A questionnaire was administered by trained interviewers for information about environmental adverse factors contact of wife and husband in and before pregnancy. Analysis probable environmental risk factors and confidential intervals of ORs for embryo loss in separate models， multiple linear regression and logistic regression model. Results：Cooking frequently during pregnancy， more daily traffic hours， decoration history in early pregnancy and toxic matter（pesticide， paint） contact of their husband during the three months before pregnancy may have adverse effects on embryo growth and development，while maternal education was a protective factor. Conclusions：Women exposed to traffic，cooking and decoration related environmental adverse factors will be potential threat to embryo normal development in early pregnancy.

Key words: Environmental pollution, Fetal growth retardation, Questionnaires, Smog, Air pollution, Air pollution