Research Progress on the Relationship between Maternal Intestinal Flora during Pregnancy and Offspring Diseases

doi:10.12280/gjfckx.20210469

Abstract

Abstract:

With the development of gene sequencing technology, the relationship between the intestinal flora and the occurrence and development of diseases has become a research hotspot in biomedical field. The research on intestinal microecology of pregnant women has attracted much attention. In order to meet the needs of fetal growth and development during pregnancy, in addition to a series of physiological adaptations in reproduction, circulation, digestion, and endocrine, the structure and quantity of the intestinal flora will also change. Factors such as maternal high-fat/low-fiber diet during pregnancy, maternal obesity, and antibiotic use during pregnancy can lead to an imbalance of the maternal intestinal microbiota, which may increase the risk of obesity, immune system diseases, nervous system diseases in the offspring. Therefore, detection of the intestinal micro-organisms in pregnant women at the right time can timely intervene and regulate the dysfunctional intestinal flora. At the same time, enhancing health education for pregnant women can reduce the risk of various diseases among the offspring and improve the overall physical quality of the population.

Key words: Gastrointestinal microbiome, Pregnant women, Obesity, Immune system diseases, Nervous system diseases

WANG Yu, ZHAN Jia-mei, LUO Xiao-hong. Research Progress on the Relationship between Maternal Intestinal Flora during Pregnancy and Offspring Diseases[J]. Journal of International Obstetrics and Gynecology, 2022, 49(1): 67-70.

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