Abstract: MicroRNA（miRNA） is a type of small evolutionarily conserved non-coding RNAs of 21-23 nucleotides in length that act as post-transcriptional regulators which involves in fundamental cell processes，such as，differentiation，proliferation and death. Recently，it has become clear that alterations in the expression of miRNAs contribute to the pathogenesis and progression of several human malignancies，such as colorectal cancer, cervical cancer, ovarian cancer, and so on. MiRNAs dysregulated expression plays an important role in ovarian cancer pathogenesis，metastasis， resistance and prognosis. They might be used as a noninvasive diagnostic and prognostic biomarker in ovarian cancer，and provide a new clinical thought for the analysis of chemotherapy drug resistance and individualized therapy. This article reviews the functions of miR-200 families,let-7 families and miR-119a, which are frequently dysregulated in ovarian cancer.

Key words: MicroRNAs, Ovarian neoplasms, Carcinoma, Neoplasm metastasis, Drug resistance, neoplasm