Journal of International Obstetrics and Gynecology ›› 2015, Vol. 42 ›› Issue (2): 201-203.

• 论著 • Previous Articles     Next Articles

Explore the Relationship between Endometrial Polyp Characteristics and Abnormal Uterine Bleeding and the Influence to Its Malignancy

HU Xiao-mei,GUAN Zheng,ZHOU Li,LI Jie,FAN Jun-zhen   

  1. Department of Obstetrics and Gynecology(HU Xiao-mei,GUAN Zheng,LI Jie),Department of Pathology(FAN Jun-zhen),Chinese PLA General Hospital,Beijing 100853,China;Department of Obstetrics and Gynecology,Chinese PLA 477 Hospital,Xiangyang 441003,Hubei Province,China(ZHOU Li)
  • Received:1900-01-01 Revised:1900-01-01 Published:2015-04-15 Online:2015-04-15
  • Contact: GUAN Zheng

Abstract: Objective: To evaluate the relationship between endometrial polyp(EP) characteristics and abnormal uterine bleeding, and analyze the influence to its malignancy. Methods:Retrospectively collect cases from January 2010 to June 2013 who received hysteroscopy and confirmed diagnosis as endometrial polyps in our hospital. Review and summarize polyp number and size of each case, and analyze the relationship between them and abnormal uterine bleeding. By pathology results, the polyp patients were divided into benign polyp and potentially malignant or malignant polyps. Analyze the relationship between the various risk factors associated with malignant polyps and malignant potential. Results:Of the included 754 cases, 38.59%(291/754) of patients with bleeding symptoms. Probability of multiple polyps and solitary polyp with bleeding were 44.26%(135/305) and 34.74%(156/449), and the difference was statistically significant(χ2=6.94,P<0.01). In 449 patients with solitary polyp, probability of large(size>10 mm) and small polyp(size <10 mm) with bleeding were 38.69%(106/274) and 28.57%(50/175), and the differene was statistically significant(χ2=4.82,P<0.05). Among polyp patients, 2.92%(22/754) of precancerous lesions, 3.18%(24/754) of cancerous. By Logistic analysis, the factors of postmenopause, polyps diameter>10 mm, multiple polyps and merging bleeding symptoms have a significant influence on precancerous and cancerous polyps(P<0.01). Conclusions:Bigger(>10 mm) or multiple polyps may be the risk factors and have a higher probability of abnormal uterine bleeding manifestations. Menopause,polyp diameter>10 mm, multiple polyps, abnormal uterine bleeding are risk factors for malignant polyps.

Key words: Endometrium, Polyps, Uterine hemorrhage, Menopause, Risk factors