Journal of International Obstetrics and Gynecology ›› 2018, Vol. 45 ›› Issue (2): 212-216.

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Advances in the Aapplication of Arterial Embolization in Management of Gestational Trophoblastic Neoplasia

YANG Ting-ting,YUE Xiao-ni,LU Xin   

  1. Obstetrics & Gynecology Hospital of Fudan University,Shanghai 200011,China
  • Received:2018-01-30 Revised:2018-03-02 Published:2018-04-15 Online:2018-04-15
  • Contact: LU Xin,E-mail:xinludoc@163.com E-mail:xinludoc@163.com

Abstract: Gestational trophoblastic neoplasia (GTN) can invade and destroy blood vessels,early appearance of distant blood metastasis,prone to hemorrhage,endangering the life of patients. With the continuous development of radioactive interventional techniques in recent years, arterial embolization therapy is more and more applied in the treatment of GTN. As an alternative to surgical treatment, in the treatment of uterine lesions and metastatic lesions, safe and efficient, the treatment of arterial embolization can preserve the fertility function of women with fertility requirements. There is a risk of chronic or severe bleeding in uterine arteriovenous fistula, color doppler ultrasonography is the preferred screening method for arteriovenous fistula, enhanced computed tomography (CT) and magnetic resonance imaging (MRI) has high specificity, but now selective pelvic arteriography is still the gold standard for diagnosis. Theoretically good intubation technique, accurate positioning, and the reasonable choice of embolization agent, control the embolization agent dose and injection rate can prevent embolization agent into the ovary, will not affect ovarian and reproductive functions. The treatment of arterial embolization will not affect the efficacy of subsequent systemic chemotherapy. Positive and accurate assessment of arterial embolization before treatment, the postoperative attention to the possible complications and active intervention can improve the safety and efficacy of treatment. This artical is to summarize the arterial embolization therapy on the effect of acute bleeding, arteriovenous fistula, the choice of embolic agent, subsequent chemotherapy, fertility and postoperative complications of GTN.

Key words: Gestational trophoblastic neoplasms, Embolization, therapeutic, Blood loss, surgical, Arteriovenous fistula, Fertility