Journal of International Obstetrics and Gynecology ›› 2019, Vol. 46 ›› Issue (5): 485-489.

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Factors Related to Pre-Eclampsia after Pregnancy with Assisted Reproductive Technology

LIU Ying, WANG Chen-hong   

  1. Department of Obstetrics, Shenzhen Hospital of Southern Medical University, Shenzhen 518110, China
  • Received:2019-03-25 Revised:2019-04-13 Published:2019-10-15 Online:2019-10-21
  • Contact: WANG Chen-hong, E-mail: szwangchenhong@vip.163.com E-mail:940143896@qq.com
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Abstract: Pre-eclampsia is one of the main reasons that seriously affect the health of mother and infant and cause their death. Assisted reproductive technology (ART) is a risk factor for pre-eclampsia. As infertility patients increases year by year ,the proportion of pregnancies obtained through ART is increasing, and the incidence of pre-eclampsia is also increasing. Recent studies at home and abroad have found that endometriosis, polycystic ovary syndrome, obesity, multiple embryo transfer, frozen embryo transfer, oocyte donation pregnancy, elevated estradiol peak during implantation, and low concentration human chorionic gonadotropin in early pregnancy are risk factors for pre-eclampsia, while progesterone is a protective factor for pre-eclampsia. These factors affect the development of pre-eclampsia alone or in combination. Early identification of risk factors for pre-eclampsia, early prevention and early intervention are the key to reduce pre-eclampsia morbidity and improve maternal and infant adverse outcomes. This article reviews the related factors of assisted reproductive pregnancy complicated with pre-eclampsia, and provides important reference for future perinatal health care of assisted reproductive pregnancy.

Key words: Pre-eclam, Fertilization in vitro, Embryo transfer, psia, Reproductive technology, assisted Infertility, female, Risk factors

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