Abstract: Long non-coding RNA (lncRNA) is a kind of RNA molecule with a length of more than 200 nucleotides. Because there is no open reading frame, it can′t encode protein. It was thought to be the "noise" in the process of gene transcription and was ignored by scholars. With the progress of epigenetics technology in recent years, lncRNA is found to play an important role in the pathogenesis of human disease. Because of its great value, it has become a hot research topic of many scholars. It has been confirmed that lncRNA molecule expression level is related to the occurrence and development, drug resistance in a variety of human tumor disease. It is expected to become a promising new tumor marker and therapeutic target in the future, and explore new therapeutic approaches for tumor treatment. In recent years, the research results of lncRNA in gynecological tumors have been reviewed, so as to provide help for the future research on the relationship between lncRNA and tumors and lay a foundation for the better development of targeted therapy for tumors.

Key words: RNA, neoplasm；, Long non-coding RNA；, Uterine cervical neoplasms；, Endometrial neoplasms；, Ovarian neoplasms