Risk and Clinical Characteristics of Thrombotic Disease in Patients with Adenomyosis

doi:10.12280/gjfckx.20211090

Abstract

Abstract:

Adenomyosis is one of the most common benign diseases in gynecology. The clinical manifestations of adenomyosis are dysmenorrhea, menorrhagia and infertility, which seriously affect the quality of life of patients. In recent years, domestic and foreign scholars have reported more than 30 cases of thrombotic disease in patients with adenomyosis, including cerebral infarction, disseminated intravascular coagulation and venous thromboembolism, most of which occurred during menstruation. After analyzing the characteristics of these patients, it was found that the risk factors for thrombotic disease in patients with adenomyosis included inflammation, increased tissue factor expression, increased blood CA125 level, menorrhagia and enlarged uterine. Once thrombotic diseases occur in women with adenomyosis, it will increase the difficulty of clinical diagnosis and treatment. Understanding the changes of coagulation function in patients with adenomyosis and being alert to the risk of thrombotic diseases will help us to improve the accuracy and safety for diagnosing and treating adenomyosis.

Key words: Adenomyosis, Venous thromboembolism, Cerebral infarction, Disseminated intravascular coagulation, Hysterectomy

ZHANG Hui-yuan, WANG An-qi, WANG Xia, ZHU Shu, WANG Xiu-li. Risk and Clinical Characteristics of Thrombotic Disease in Patients with Adenomyosis[J]. Journal of International Obstetrics and Gynecology, 2022, 49(3): 250-255.

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