Abstract: Vulvovaginal candidiasis（VVC）is a common disease, occurring mostly in women of childbearing age. Currently available options for the treatment of VVC include local and oral therapy. Both alternatives are effective. The availability of numerous antifungal drugs for topical administration makes the selection quite challenging. Now it is generally considered that azoles is the preference, with nystatin, amphotericin B and boric acid considered as second-line alternatives, with lactobacillus, oils and antihistamine as adjuvant alternatives. Unconventional approaches may also be regarded as suitable in patients refractory to usual treatments. When treatment of VVC, some other important issues should be taken into consideration, such as pregnancy, menopause, drug hypersensitivity, women’s preference and so on.

Key words: Candidiasis, vulvovaginal, Candida albicans, Candida glabrata, Drug therapy