Abstract: Objective：Detection the expression of miR-210 and investigation its roles in epithelial ovarian cancer（EOC）. Methods：Poly（Ａ）-RT-qPCR was used to detect the expression of miR-210 in epithelial ovarian cancers and benign epithelial ovarian cysts and normal ovarian tissues. Results：miR-210 in ovarian cancer group was lower than that of benign ovarian tumors and normal ovarian group，significant difference among the three groups（F=893.213，P=0.000）. With the progress of the clinical staging of ovarian cancer tissues and tissue differentiation，miR-210 expression there has a downward trend. Conclusions：Our data suggest that miR-210 expressed lowerly in EOC，it might play an important role as an anti-oncogene in the genesis and development of epithelial ovarian cancer. It is bound with lymphatic metastasis，stages of ovarian cancer and tissus grading.

Key words: Ovarian neoplasms, MicroRNAs, Reverse transcriptase polymerase chain reaction, Genes, tumor suppressor