国际妇产科学杂志

国际妇产科学杂志 ›› 2011, Vol. 38 ›› Issue (3): 197-200.

• 综述 • 上一篇    下一篇

妊娠期糖尿病发病机制及对母婴的影响

揭金花,许榕仙   

  1. 350101 福州，福建卫生职业技术学院（揭金花）；福建医科大学公共卫生学院营养与保健医学系（许榕仙）
  • 收稿日期:1900-01-01 修回日期:1900-01-01 出版日期:2011-06-15 发布日期:2011-06-15
  • 通讯作者: 许榕仙

Research on Pathogenesis of Gestational Diabetes Mellitus and its Influence on Maternal and Infant

JIE Jin-hua，XU Rong-xian   

  1. Fuzhou 350101, China（JIE Jin-hua）；Department of Nutrition and Health Care Medicine, School of Public Health，Fujian Medical University，Fuzhou 350000， China（XU Rong-xian）
  • Received:1900-01-01 Revised:1900-01-01 Published:2011-06-15 Online:2011-06-15
  • Contact: XU Rong-xian

PDF (PC)

5987

被引次数

41

摘要： 年龄、肥胖、种族、不良孕育史和糖尿病家族史是影响妊娠期糖尿病（gestational diabetes mellitus，GDM）的主要因素。胰岛素抵抗是其主要发病机制。GDM对母儿影响的严重程度与病情及血糖控制情况密切相关，主要表现为妊娠期高血压、羊水过多、巨大儿、早产、难产及软产道损伤、剖宫产等发生率明显增高，还可增加围生儿发病率、死亡率，甚至增加儿童期肥胖及代谢综合征、母亲患糖尿病风险等。

关键词: 妊娠, 胎儿, 糖尿病, 糖尿病, 妊娠, 妊娠并发症

Abstract: Risk factors of gestational diabetes mellitus（GDM）include age，obesity，ethnicity，adverse obstetrical and neonatal outcomes，and family history of diabetes. Insulin resistance plays a main role in GDM. Impact of GDM on mothers and fetals is intimately related to levels of glycaemic control. Women with GDM are increased risk of pre-eclampsia，polyhydramnios，shoulder dystocia or cephalopelvic disproportion，injury of birth canal， caesarean delivery and diabetes after years，while their infants tend to experience higher rates of macrosomia， preterm birth，morbidity and mortality. The offspring of these women are also at increased risk of obesity and metabolism syndrome in childhood.

Key words: Pregnancy, Fetus, Diabetes mellitus, Diabetes, gestational, Pregnancy complications