Factors Related to Enhanced Radiosensitivity of Recurrent Epithelial Ovarian Cancer

doi:10.12280/gjfckx.20200534

Abstract

Abstract:

Ovarian cancer has an insidious onset, and most patients are diagnosed in the middle and advanced stages. The first-line treatment of ovarian cancer is still based on surgery, supplemented by chemotherapy and radiotherapy. Ovarian cancer has a high recurrence rate, with more than 80% of recurrences even after complete remission after treatment. Radiotherapy can effectively control symptoms, relieve tumor development, improve quality of life and prolong progression-free survival for recurrent epithelial ovarian cancer, advanced lesions and lesions at special sites (such as pelvic wall, lymph nodes, etc.). However, due to the resistance of ovarian cancer cells to radiation, the efficacy of radiotherapy for ovarian cancer is affected. Therefore, improving the radiosensitivity of ovarian cancer cells can improve the efficacy of radiotherapy for ovarian cancer. The aim of this study was to review the factors associated with enhanced radio sensitivity in recurrent epithelial ovarian cancer.

Key words: Ovarian neoplasms, Neoplasm recurrence, local, Radiotherapy, Radiation tolerance, Pharmaceutical preparations, Genes, Recurrent epithelial ovarian cancer

YU Xiao-yun, LI Rui-yan, HE Ling-ling, FENG Shu-jie, WANG Hai-lin. Factors Related to Enhanced Radiosensitivity of Recurrent Epithelial Ovarian Cancer[J]. Journal of International Obstetrics and Gynecology, 2021, 48(2): 154-158.

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