Abstract:

Intrauterine adhesions, also known as Asherman syndrome, is mostly secondary to transuterine surgery or infection. The main clinical manifestations are abnormal menstruation and fertility complications. With the advancement of society and medical technology, the popularity of hysteroscopy and the increasing number of intrauterine operations, the incidence of intrauterine adhesions has gradually increased. Accordingly, the female infertility rate has increased. Since the incidence of re-adhesion after transcervical resection of adhesion is relatively high, and the pregnancy rate and live birth rate are low, postoperative application of various anti-adhesion materials has become the focus of attention of gynecologists. At present, the common anti-adhesion materials include intrauterine devices, biological dressings, saccule, amnion, hyaluronic acid gel, tissue scaffolds, stem cells, and so on. Using these materials to isolate the wounds in the uterine cavity from each other to reduce the incidence of re-adhesion and the degree of endometrial fibrosis. Summarizing the application of anti-adhesion materials in animal experiments and clinical research, which can provide a basis for choosing appropriate treatments for patients with intrauterine adhesions after surgery.

Key words: Tissue adhesions, Intrauterine devices, Saccule and utricle, Amnion, Biological dressings, Stem cells, Tissue scaffolds, Hyaluronic acid gel