Journal of International Obstetrics and Gynecology

Journal of International Obstetrics and Gynecology ›› 2011, Vol. 38 ›› Issue (5): 402-406.

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Mucosal Dendritic Cells in the Genital Tract Immuology

LI Li，HUANG Li-li   

  1. Department of Gynecologic Oncology，Zhejiang Cancer Hospital，Hangzhou 310022，China（LI Li）；Women’s Hospital，School of Medicine，Zhejiang University，Hangzhou 310006，China（HUANG Li-li） Corresponding author：HUANG Li-li，E-mail：fbhuanglili@163.com
  • Received:1900-01-01 Revised:1900-01-01 Published:2011-10-15 Online:2011-10-15
  • Contact: HUANG Li-li

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Abstract: Dendritic cells（DCs）are the most potent antigen-presenting cell（APC）and play important roles in innate immune defense as well as in adaptive immunity. The female genital tract is immunologically unique in its requirement for immunity against a wide array of pathogens and for tolerance the allogeneic sperm and the semi-allogeneic embryo. This review summarizes the latest advances in our understanding of DCs in the genital tract with respect to their subsets，lineage，and function.

Key words: Dendritic cells, Genitalia, female, Immunity, mucosal, Pregnant women