Abstract: The diagnostic criteria of gestational diabetes mellitus has being changed continuously. Based on the hyperglycemia and adverse pregnancy outcome study, most international academic organizations including World Health Orgnization and Ministry Heath of China published new criteria, while there are still some arguments. After introduced the development of the diagnostic criteria and risk factors, the article presented the study of metformin in gestational diabetes the offspring followup and proposed to adopt comprehensive intervention to face the challenges to our clinical management in China.

Key words: Diabetes, gestational, Diagnosis, Risk factors, Universal precautions