Journal of International Obstetrics and Gynecology ›› 2014, Vol. 41 ›› Issue (6): 617-620.

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The Current Status of Nanomaterials in Female Pelvic Floor Reconstruction

HOU Min,WU Qing-kai   

  1. Department of Obstetrics and Gynecology,Shanghai Sixth People′s Hospital,School of Medicine,Shanghai Jiao Tong University,Shanghai 200233,China
  • Received:1900-01-01 Revised:1900-01-01 Published:2014-12-15 Online:2014-12-15
  • Contact: WU Qing-kai

Abstract: Pelvic floor dysfunction(PFD) is the inability of the pelvic floor to fulfil its supportive role to the pelvic organs and/or its inability to allow these organs to function normally,including urinary incontinence(UI), pelvic organ prolapse(POP) and fecal incontinence(FI). PFD pathogenesis is not clear,the main objective of treatment is to restore the anatomy and function of the pelvic organs,surgery is the most important treatment for PFD. Due to polypropylene mesh erosion and rejection,scholars are still exploring histocompatibility better pelvic floor reconstruction. Nanomaterials can mimic the nanoscale properties of native extracellular matrix and facilitate cell attachment differentiation and proliferation to guide tissue repair and regeneration. In this review, we discuss the classification,properties, nanotechnology, study status, potential applications of nanomaterials on the field of pelvic reconstruction.

Key words: Nanostructures, Nanotechnology, Prolapse, Urinary incontinence, Pelvic floor, Reconstructive surgical procedures