Journal of International Obstetrics and Gynecology ›› 2017, Vol. 44 ›› Issue (6): 671-676.

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Research Progress of Sentinel Lymph Node in Endometrial Carcinoma

WANG Tian,HU Yuan-jing   

  1. Tianjin Medical University,Tianjin 300070,China(WANG Tian);Tianjin Central Hospital of Gynecology Obstetrics,Tianjin 300100,China(HU Yuan-jing)
  • Received:2017-09-08 Revised:2017-11-29 Published:2017-12-15 Online:2017-12-15
  • Contact: HU Yuan-jing,E-mail:tdjhyj@hotmail.com E-mail:1057185178@qq.com

Abstract: Sentinel lymph nodes (SLN) mapping as a new technology can show suspicious metastasis of lymph nodes, the current treatment of endometrial carcinoma has a good application prospect, this paper reviews the existing literature of endometrial cancer sentinel lymph node, understanding the background of the sentinel lymph node and multiple recognition technology, application value and micrometastases, etc., and analyzes it with systematic lymphadenectomy for patients survival quality, the influence of the period, prognosis, is the future development direction of dispute and related problems. Conclusion: indoline green (ICG) cervical injection can accurately assess the state of pelvic and partial abdominal aortic lymph nodes, and the false negative rate can reach < 5%. The detection rate of the sentinel lymph node at the abdominal aorta was about <5%, and the probability of the metastasis of the abdominal aortic lymph node was about 0.8%-1%, and the metastasis probability of the patients with endometrial cancer and the high level was 3%. SLNS through pathology staging detection can well predict the small volume of lymph node metastasis (ITCs and micrometastases), small volume transfer patients have better prognosis, after treatment with auxiliary progression-free survival (should get rid of the word) incidence similar to not shift patients. SLN can improve the survival quality of patients, and low-grade endometrial carcinoma can only be resected with SLN, while patients with high risk factors are reasonable in SLN removal, but the safety is open to discussion.

Key words: Endometrial neoplasms, Lymph nodes, Radioactive tracers, Neoplasm metastasis, Prognosis