Abstract: Objective：To investigate the suitable surgical method for cervical incompetence during pregnancy. Methods：A total of 67 patients with cervical incompetence during pregnancy from July 2013 to July 2017 in our hospital were enrolled in the retrospective analysis, had naturally conceived single birth with complete follow-up data after laparoscopic uterine isthmus cerclage or transvaginal cervical cerclage were divided into two groups according to two different surgical methods to compare the clinical effect. 30 patients in the research group were treated with laparoscopic uterine isthmus cerclage, and the other 37 patients in the control group treated with transvaginal cervical cerclage. Results：Operation time of the research group was higher than the control group [(48.13±1.85) min vs. (16.24±2.29) min, P=0.00]. The research group had got a longer average pregnancy period than control group [(37.07±3.15) weeks vs. (29.11±6.43) weeks, P=0.00]. Postoperative abortion rate (6.67%) and preterm birth rate (13.33%) of research group were obviously lower than that of the control group (P＜0.05). The term infant rate of research group (80.00%) was higher than that of the control group (P＜0.05). The hospital stay of the research group were less than that of the control group [(3.17±0.42) d vs. (5.32±1.63) d, P=0.00]. The complication rate of observation group was 0%, and the control group was 13.51%. The difference was significant (P＜0.05). There is no statistical significant difference in terms of the hemorrhage amount during operation between the two groups. Conclusions：Laparoscopic uterine isthmus cerclage in treatment of cervical incompetence at first trimester has better clinical effect and fewer post-operative complications than transvaginal cervical cerclage at second trimester. It has higher feasibility and security. It is worth promoting clinically.

Key words: Cervical cerclage, Uterine cervical incompetence, Treatment outcome, Pregnant women, Retrospective studies