Abstract: Pelvic floor dysfunction is a common and frequently-occurring disease in middle-aged and elderly women. Patch implantation is an ideal surgical treatment. Polypropylene-based filler material has been suggested as a common method to rehabilitate the pelvic support structure, but there are complications such as exposure and erosion. Biogenic patches have good tissue compatibility but insufficient mechanical properties. Tissue engineering is a new discipline which the applied the principles and techniques of life sciences and engineering, based on a correct understanding of the relationship between tissue structure and function in normal and pathological conditions of mammals, researching and developing biological substitutes of function and morphology to repair, maintain and promote various tissues or organs damage of the human body. Tissue engineering technology is applied to the treatment of pelvic organ prolapse, which can meet the mechanical requirements of pelvic floor support, and its biocompatibility is superior to traditional polypropylene patch, and can promote tissue repair to a certain extent. It′s the urgent need for patch implantation therapy. This article outlines the research progress of tissue engineering, to understand and guide the application of tissue engineering in the treatment of pelvic organ prolapse.

Key words: Tissue engineering, Stem cells, Seed cells, Biological scaffold material, Stents, Biocompatible materials, Pelvic floor dysfunction