Abstract: Port site metastasis (PSM) is a special complication after laparoscopy. The incidence of the disease is associated with the malignancy of the disease, the types of tumors, the histologic type, the FIGO stage, the ascites and the purpose of laparoscopy. The highest incidence of PSM is the ovarian cancer in the gynecologic malignant tumor, and advanced cancer, massive ascites, and malignant tumor rupture are closely related to PSM. The occurrence of PSM is related to tumor biological characteristics, surgical techniques, CO2 and pneumoperitoneum, the use of energy instruments, host immune response, and so on. Selecting the appropriate cases, reducing tissue damage during the intraoperative biopsy, strictly obey the principle of surgical non-tumor, avoid the leakage or sudden release of CO2 gas during the operation, shorten the pneumoperitoneum time, flushing the abdominal cavity, the instruments and the port sites at the end of surgery, suturing puncture holes above 5 mm are the key methods to prevent the occurrence of PSM.

Key words: Genital neoplasms, female, Laparoscopes, Neoplasm metastasis