Abstract: Platelet-rich plasma (PRP) is a kind of biological agent derived from autogenous blood. Platelet bioactivity plays an important role in inflammation, cell proliferation and tissue healing. Therefore, PRP products have been used to promote the healing of skin, bone and muscle injury and regulate inflammation. Intrauterine adhesion, which damage the basal layer of endometrium, causes infertility and amenorrhea, etc., so causes a great deal of trouble for women with fertility requirement. The treatment of intrauterine adhesion requires surgical separation of adhesions, prevention of postoperative recurrence, repair of endometrium, and improvement of fertility outcome. PRP can regulate inflammation and promote tissue healing, which brings new hope to patients with intrauterine adhesion. Since PRP comes from autogenous blood, it is safe in clinical application. This paper reviews the overview, mechanism, clinical application of PRP and its role and status in intrauterine adhesion.

Key words: Uterine diseases；, Tissue adhesions；, Platelet-rich plasma；, Pregnancy；, Infertility, female；, Endometrial hyperplasia